Topic: John Walters

The hosts compare the current debate format to the 1960 Kennedy-Nixon debate, which also lacked a live audience. They recall famous debate moments, such as Ronald Reagan's "youth and inexperience" quip against Walter Mondale and Lloyd Bentsen's "you're no Jack Kennedy" line to Dan Quayle.

The show concludes with a clip of Joe Biden making confusing remarks about nurses at Walter Reed breathing into his nostrils. Adam Curry and John C. Dvorak sign off, reminding listeners of the next show on Sunday. The episode ends with a series of listener-produced music mixes and satirical "Orange Man Bad" network imaging.

Former drug czars Gil Kerlikowske and John Walters discussed the accelerating death toll from synthetic opioids on PBS NewsHour. They noted that fentanyl and heroin are now killing more Americans annually than gun violence and car accidents combined. The discussion highlights the shift from prescription pill abuse to criminally produced synthetics often sourced from international organizations.

The hosts read a series of birthday requests and perform a "de-douching" for a new donor. They acknowledge several listeners from around the world, including Sweden and Canada, and share a humorous note about a father's love for history and Fox News.