Topic: Potency

A listener email provides a detailed breakdown of opiate strengths, noting that pharmaceutical fentanyl is expensive and usually distributed via patches or lollipops. The hosts contrast this with "methylfentanyl," a much cheaper and more potent analog. They speculate that this version is being produced in Syria or Turkey and smuggled into the U.S. as a chemical additive for heroin.

The hosts reflect on the evolution of No Agenda, arguing that the current "deep analysis" of paperwork is superior to the show's earlier, more "flailing" episodes. They briefly discuss the increased potency of modern marijuana compared to the "doobies" of the past, concluding that they prefer their current sober analytical approach.

Adam Curry debunks the "meme" that modern marijuana is significantly more dangerous or "harder" than the varieties available in the 1960s. Drawing on over a decade of personal experience as a heavy smoker, he argues that while potency may vary, the fundamental nature of the drug remains the same and is far less harmful than prescribed antipsychotics.