4 chapters across the catalog
Reproducibility Crisis, The Economist and Scientific Study Failures
The Economist reports on the "reproducibility crisis" in modern science, noting that many seminal studies cannot be replicated. Researchers at Bayer Healthcare successfully reproduced only 25% of 67 major studies in drug discovery. The hosts argue that the lack of motivation for reproducible studies undermines the credibility of the scientific community.
Scientific Reproducibility Crisis in Cancer Research
The Reproducibility Project at the University of Virginia attempted to replicate five landmark cancer biology studies, successfully confirming only two. This crisis in the scientific community calls into question the validity of peer-reviewed literature and the reliability of the scientific process.
Scientific Reproducibility Crisis and Chatham House Rules
The medical journal The Lancet has highlighted a crisis in scientific research, noting that a significant portion of published studies are unreproducible due to data manipulation and a broken peer review process. The hosts discuss how these issues are being debated under "Chatham House Rules," which allow for the use of information while protecting the identity of the speakers.
Intermittent Electronic Failures and Toyota's Reproducibility Problem
Akio Toyoda and other executives testified that many reported cases of unintended acceleration are non-reproducible in laboratory settings. This intermittent nature of electronic failures complicates the investigation. Congresswoman Eleanor Holmes Norton criticized this explanation, accusing the company of potentially blaming victims for the mechanical or software malfunctions.
