Topic: Endocannabinoid

The biological function of the endocannabinoid system is explained, showing how THC mimics compounds naturally produced by the human brain to regulate neurotransmitters. Despite popular petitions for legalization, President Obama has historically dismissed the issue. The hosts advise listeners to save heirloom seeds to prevent corporate control of the plant by companies like Monsanto as legalization spreads.

A clinical drug trial in Rennes, France, results in one person being declared brain dead and five others hospitalized. The drug, intended to target the endocannabinoid system for pain management, likely caused the neurological damage due to a massive dosage error or "hot dose" during the testing phase.